Published On: Wed, Jan 27th, 2016

Constant stress and anxiety can elevate depression



Recently new research study has revealed that people who experienced constant stress and anxiety may be at an enlarged peril for developing depression and even dementia.

Having anxiety, fear and stress are believed a normal part of life when it is irregular and momentary, for example, feeling anxious and stressed prior to an exam or a job interview.

Researchers at Rotman Research Institute at Baycrest Health Sciences in Canada stated that Nevertheless when those sensitive emotional reactions turn more recurrent or constant, they can considerably impede with everyday living activities, for example, work, school and relationships.

Persistent stress is a pathological condition that is because of extended activation of the usual sharp physiological stress retort, which can cause chaos on immune, metabolic and cardiovascular systems, and direct to atrophy of the brain’s hippocampus — which is critical for long-term memory and spatial navigation.

Researchers tested latest proof from studies of stress and fear situation in animal models and neuroimaging studies of stress and anxiety in healthy individuals and in the clinical populace. They examined particularly at key compositions in the neurocircuitry of fear and anxiety — amygdala, medial prefrontal cortex and hippocampus — which are contacted all through contact to constant stress.

The researchers found alike patterns of abnormal brain action with fear/anxiety and chronic stress — particularly an overactive amygdala (connected with emotional reactions) and an under-active PFC (thinking regions of the brain that assist control emotional reply by cognitive appraisal). The results illustrated that there is an ‘extensive overlap’ of the brain’s neurocircuitry in all three states.

Linda Mah from Baycrest’s Rotman Research Institute stated that “Pathological anxiety and chronic stress are associated with structural degeneration and impaired functioning of the hippocampus and the prefrontal cortex (PFC), which may account for the increased risk of developing neuropsychiatric disorders, including depression and dementia,”

She further added that “Antidepressant treatment and physical activity have both been found to increase hippocampal neurogenesis,”

About the Author

Sidra Muntaha

- Sidra Tul Muntaha is a journalist (MA-Mass Communication and M.Phil in Mass Communication) based in Lahore. She is working as an editor at fashion, style and entertainment in the section of the Kooza. She writes fashion and entertainment articles for The Kooza News.