Published On: Wed, Jul 27th, 2016

Menopause, insomnia can make you aged



It is revealed that hot flashes and sleepless nights can make you older than your actual age.

Two different UCLA research studies recommend that menopause and insomnia can boost women’s jeopardy for aging-related diseases and earlier death.

Steve Horvath, who is the senior researcher of the study, has stated that “For decades, scientists have disagreed over whether menopause causes aging or aging causes menopause,” Steve Horvath further added “It’s like the chicken or the egg: which came first? Our study is the first to demonstrate that menopause makes you age faster.”

Judith Carroll, who is the first researcher of the study, stated “Not getting restorative sleep may do more than just affect our functioning the next day; it might also influence the rate at which our biological clock ticks,” Judith Carroll continued “In the women we studied, those reporting symptoms such as restless sleep, waking repeatedly at night, having difficulty falling asleep, and waking too early in the morning tended to be older biologically than women of similar chronological age who reported no symptoms.”

To conduct the research, both research studies employed a “biological clock” made by Horvath, which has turned an extensively employed technique for following the epigenetic shift in the genome. Epigenetics is the research study of alterations to DNA wrapping that power which genes are spoken but don’t affect the DNA series itself.

In the menopause research, Horvath and initial researcher Morgan Levine tracked methylation, a chemical biomarker connected to aging, to examine DNA samples from over 3,100 women registered in four great research studies, involving the Women’s Health Initiative (WHI) a main 15-year research plan that deals with the much widespread reasons of death, disability and bad quality of life in postmenopausal women.

They calculated the biological age of cells from blood, saliva and within the cheek, to discover the association amid every woman’s sequential age and her body’s biological age.

Horvath further stated that “We discovered that menopause speeds up cellular aging by an average of 6 percent,” Horvath told, “That doesn’t sound like much but it adds up over a woman’s lifespan.”

In the slumber research study, Carroll and her coworkers depicted their data from over 2,000 women in the WHI. Employing the epigenetic clock, they discovered that postmenopausal women with five insomnia signs were almost two years elder biologically than women the similar sequential age with no insomnia signs.

Carroll continued “We can’t conclude definitively from our study that insomnia leads to the increased epigenetic age, but these are powerful findings,” Carroll added by saying that “In the future, we will need to carry out studies of the same individuals over an extended period of time to determine cause-and-effect relationships between biological age and sleep disorders.”

The double verdicts come out in the Proceedings of the National Academy of Sciences and Biological Psychiatry.


About the Author

Sidra Muntaha

- Sidra Tul Muntaha is a journalist (MA-Mass Communication and M.Phil in Mass Communication) based in Lahore. She is working as an editor at fashion, style and entertainment in the section of the Kooza. She writes fashion and entertainment articles for The Kooza News.